In summary, riboflavin (vitamin B2) is essential for the biochemistry of the nervous system, functioning as a cofactor in redox reactions, supporting ATP production, enhancing antioxidant defense, and promoting overall cellular health ( 4 Vitamin B3 Vitamin B3, commonly known as niacin, is predominantly found in meats, cereals, dairy products, fish, and eggs, and the recommended daily intake for niacin ranges from 15 mg/day to 20 mg/day for humans ( Niacin is crucial for the biochemistry of the nervous system, playing a significant role in energy metabolism, antioxidant activities, and the synthesis of essential molecules for neuronal function, such as acting in dopamine synthesis ( Nicotinamide adenine dinucleotide (NAD) is a co-substrate for various enzymes, such as sirtuins, polymerases, and cyclic ADP-ribose synthesis ( Niacin also contributes to the synthesis of neurotransmitters, such as serotonin, a derivative of tryptophan, which is pivotal for mood regulation and various neurological functions, such as sleep and appetite, besides impacting cognitive and executive functions (50)
Arachidonic Acid Arachidonic acid is converted to prostaglandin H2 (PGH2) via two forms of cyclooxygenase: Cyclooxygenase-1 (COX-1) and Cyclooxygenase-2 (COX-2)
Proc Natl Acad Sci USA (2021) 118(11):e2023265118
doi: 10.1016/0014-2999(90)90204-J
They can block molecules that promote angiogenesis or cancer cell growth, preventing cell proliferation
